30sec Time Lapse of DC Snow

8 February 2010

Here is a neat video of the DC snowfall. 30 inches in 30 hours in a 30 sec time lapse.

Diabetes – Handing Down the Genes

8 February 2010

#diabetes >> (www.diabeteshealth.com) by Olivia Grider Feb 4, 2010

This is the beginning of our three part series “Handing Down the Genes.”  Part I: “When to Worry-and When Not to-About Your Child’s Increased Risk for Diabetes.”

The little things are adding up again, making me worry. First, the bed wetting. It’s not that he has started wetting the bed; it’s that he never stopped. And he just turned seven. And it’s worse lately. Even the “Good Nites Underpants for Big Boys” aren’t sparing the sheets and blankets. He’s an extremely deep sleeper, so that’s probably the reason. Or…

Then there’s the way he’s always thirsty, the comments about how skinny he’s gotten from relatives who haven’t seen him in a year, the irritability, and now, even after a large glass of sweet tea (usually not allowed), definite lethargy. The recent baseball games and practices could account for the thirstiness, he could be losing baby fat, and he did stay up really late last night, so that might be why he’s tired. Or…

I want to reach for my glucose meter, but I know how that plays out. Coaxing, bribing, crying (“No, don’t stick me with that needle!”). Then, when I give in – to avoid a chase through the house – “Momma, do I have diabetes?” Great. Now I’ve worried him.

So how are parents with diabetes supposed to balance concern over their children’s increased risk for the disease with a desire not to cause undue alarm?

I decided to start with the basics.

What are the risks, anyway?

Like most parents who have diabetes, I knew that type 1 and type 2 have a genetic element and that my children are at a higher risk of developing the disease than kids without a family history. But I didn’t know by how much my condition increased their risk.

According to the American Diabetes Association, if you’re a man with type 1 diabetes, your child has a six percent chance of developing the disease. If you’re a woman with type 1 and your child was born before you were 25, the child’s risk is four percent; if your child was born later, his or her risk is one percent. Double the odds if you developed diabetes before age 11. Your child’s risk of getting diabetes is between 10 percent and 25 percent if both you and your partner have type 1. The risk for siblings of children with type 1 is akin to having one parent with the disease. Among the general population, the odds of developing type 1 are less than one percent.

“It [the increased risk] is not necessarily a lot,” says Dr. Gabriella Grinstein, pediatric endocrinologist at the Friedman Diabetes Institute at Beth Israel Medical Center in New York. “We’re talking only a 20 percent chance, assuming that both parents have it.” She notes that over 75 percent of the children she treats for type 1 have no family history of the disease.

Type 2 diabetes is more common among the general population – the current risk is about 10 percent, says Dr. Henry Prost, endocrinologist and medical director of the Baylor Diabetes Center in Dallas – and it’s rising. ADA estimates that one in three Americans born in 2000 will develop type 2. The tendency to run in families also is stronger in type 2. If you have type 2, Prost says, the likelihood that your child will develop the same condition is 30 to 50 percent. If both you and your partner have the disease, the risk is 50 to100 percent.

“This should be a very big concern,” Grinstein says. “With the obesity epidemic in this country, type 2 is affecting people at younger ages than in the past. Developing type 2 at 50 is much different from developing it when you’re 10 years old.” A person who gets type 2 diabetes in his or her fifties might not experience complications until age 70, she explains. But a child who gets it at 10 could have significant health issues in his or her twenties.

Preventing type 2

The good news for those with type 2 is that there are things you can do to lessen your child’s risk. Nancy Heinrich, an epidemiologist who specializes in diabetes and the founder of Growing Healthy Kids, a Vero Beach, Florida-based non-profit organization aimed at preventing childhood obesity and diabetes has some simple guidelines.

Tune in next Saturday for Part II, “Preventing Type 2 for Children” from Olivia Grider

AACE Approves New Diagnosis for Diabetes

8 February 2010
#diabetes >>Russell Phillips, PhD Feb 5, 2010

In addition to diagnosing type 2 diabetes based on fasting blood glucose levels or a glucose tolerance test, the American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) have now approved the use of A1c as an additional diagnostic criterion for type 2 diabetes.

The AACE decision was released in a position statement entitled “The AACE/ACE Statement on the Use of A1c for the Diagnosis of Diabetes”, which can be found online here. The position statement also reviews the limitations of the test, such as certain ethnic groups having marginally elevated values, which do not necessarily indicate diabetes.

The A1c or hemoglobin A1c (HbA1c) test determines the average level of blood glucose over a 3-month period.  How does that work? Red blood cells contain a protein called hemoglobin A, which is the actual carrier of oxygen in the blood. Glucose in the blood also attaches to the protein (or glycates the protein).  More glucose in the blood means more of it can to stick to the hemoglobin A protein.  Once a hemoglobin molecule is glycated, it stays that way. And since hemoglobin A can survive in the bloodstream for about 3 months, measuring the amount of glycated hemoglobin gives you an average amount of glucose in the blood over about a 3 month period. An A1c of 7.0 indicates that 7 percent of the hemoglobin A molecules are glycated.

“Using A1c will provide doctors and patients a convenient additional tool to diagnose diabetes and thereby identify more patients with it,” said Dr. Jeffrey R Garber, president of AACE, in a press release.

The most common criteria currently used to diagnose diabetes are a fasting glucose of 126 or greater, or a two-hour value on a glucose tolerance test (GTT) greater than 200. Both tests require patients to fast for a minimum of eight hours prior to being tested. The GTT is a 2-hour series of measuring glucose levels (multiple blood draws) following the administration of a large amount of glucose.

The AACE Guidelines for the Management of Diabetes use an A1c of 6.5 (meaning 6.5 percent of the hemoglobin A is glycated) or less as a goal for patients once they have been diagnosed with type 2 diabetes.

About the American Association of Clinical Endocrinologists (AACE) AACE is a professional medical organization with more than 6,000 members in the United States and 91 other countries. AACE members are physicians who specialize in endocrinology, diabetes, and metabolism. For more information about AACE, visit their web site at http://www.aace.com/.

* * *

Sources:

American Association of Clinical Endocrinologists: http://www.aace.com/

Press release http://media.aace.com/article_display.cfm?article_id=4942

Fort Madison, IA – Man Missing in River

8 February 2010

(www.connecttristates.com)

FT. MADISON, IA. — Fort Madison police and search and rescue teams have called off the search for a 22-year-old Keokuk man.

Around 2 a-m Sunday police received a report that Ray Charles Newell Dean of Keokuk had fallen through the ice along the Mississippi River, just west of Riverview Park.

Emergency crews searched the area by land and water. The search ended at 8:30 a-m.  The search was hampered by icy conditions on the water.

Dean’s body wasn’t found.  Police believe Dean was out for a walk when he walked out onto the ice about 100 feet off the shore.

NO AGENDA #172

8 February 2010

#NoAgenda For Sunday February 7th 2010
Palin Teapot Party

Discover Simple, Private Sharing at Drop.io

2 min video that will “Flip” you

8 February 2010

“There’s a flip side to everything,” the saying goes, and in 2 minutes, Derek Sivers shows this is true in a few ways you might not expect.

Derek Sivers is best known as the founder of CD Baby. A professional musician since 1987, he started CD Baby by accident in 1998 when he was selling his own CD on his website, and friends asked if he could sell theirs, too. CD Baby was the largest seller of independent music on the web, with over $100M in sales for over 150,000 musician clients.

In 2008, Sivers sold CD Baby to focus on his new ventures to benefit musicians, including his new company, MuckWork, where teams of efficient assistants help musicians do their “uncreative dirty work.”

Patients Like Me – Jamie Haywood

8 February 2010

This website in the article below (www.patientslikeme.com) is NOT just for ALS, but for a lot of other diseases. Patients especially talk about medications they are on and the side effects. Very informative. /MIke

When Jamie Heywood’s brother was diagnosed with ALS, he devoted his life to fighting the disease as well. The Heywood brothers built an ingenious website where people share and track data on their illnesses — and they discovered that the collective data had enormous power to comfort, explain and predict.

After finding out that his brother, Stephen, had the terminal illness ALS, Jamie Haywood founded the ALS Therapy Development Institute in 1999. ALS TDI is the world’s first non-profit biotechnology company and accelerated research on the disease by hiring scientists to develop treatments outside of academia and for-profit corporations. They were the first to publish research on the safety of using stem cells in ALS patients.

In 2005,Jamie and his youngest brother Ben, along with close friend Jeff Cole, built PatientsLikeMe.com to give patients control and access to their healthcare information and compare it to others like them. Its bold (and somewhat controversial) approach involves aggregating users health info in order to test the effects of particular treatments, bypassing clinical trials. It was named one of “15 companies that will change the world” by CNN Money.

Although his brother passed away in the fall of 2006, Jamie continues to serve as chairman of PatientsLikeMe and on the board of directors of ALS TDI. Jamie has raised over $50 million dollars for ALS TDI and was the subject of the biography His Brother’s Keeper, written by Jonathan Weiner. He was also featured in the documentary So Much So Fast, exploring the development of ALS TDI and the personal story of he and Stephen.

WTF?

8 February 2010

(slashdot.org)
“US government policy is that photos produced by federal employees as part of their job responsibilities are not subject to copyright in the US. But Kathy Gill writes that after originally putting official White House photos in the public domain, since January the Obama White House has been asserting that no one but ‘news organizations’ can use its Flickr photos taken by the official White House photographer, who is a US government employee. This change appears to be a heavy-handed response to last month’s controversy resulting from a billboard that implied the President endorsed The Weatherproof Garmet Co. after the company used an AP photo of the president for a Times Square billboard. However a New York law already protects individuals from unauthorized use of their image for advertising, and the billboard was quickly taken down. Gill writes, ‘Whatever the reason, the assertion of these “rights” seems to be in direct contrast to official government policy and is certainly in direct contrast to reasonable expectations by the public, given that the photos are being produced with taxpayer (i.e., public) money. Ironically, the same Flickr page that claims (almost exclusive) copyright also links to the US copyright policy statement.’”

Geo – Medicine

8 February 2010

Where you live: It impacts your health as much as diet and genes do, but it’s not part of your medical records. At TEDMED, Bill Davenhall shows how overlooked government geo-data (from local heart-attack rates to toxic dumpsite info) can mesh with mobile GPS apps to keep doctors in the loop. Call it “geo-medicine.”

Bill Davenhall has spent three decades creating useful intelligence out of what seems ordinary demographic and geographic data. In the ’70s he built the first geo-demographic models that helped some of America’s most well-known franchises expand across the nation; in the ’80s he founded a start-up market research company that developed the first national database of estimates for the demand of healthcare services.

Davenhall leads the health and human services marketing team at ESRI, the largest geographic information system (GIS) software developer in the world.

Our Behavior Conditioning Needs Changed

7 February 2010

This video is an eye opener. It is a rather long video over 20 minutes, but well worth it. /MIke

MacArthur winner Sendhil Mullainathan uses the lens of behavioral economics to study a tricky set of social problems — those we know how to solve, but don’t. We know how to reduce child deaths due to diarrhea, how to prevent diabetes-related blindness and how to implement solar-cell technology … yet somehow, we don’t or can’t. Why?

Sendhil Mullainathan

To study big questions such as “What are the measurable effects of corruption?”" Sendhil Mullainathan and his collaborators look at the day-to-day decisions made by real people, running deep-data studies on groups around the world to tease out patterns. Awarded a MacArthur “”genius”" grant in 2002, he has produced and collaborated on a string of research papers that make for a must-read CV — including a fascinating, if dispiriting, study of the corruption involved in getting a driver’s license in India.

Lately he and his team have been studying women who sell fruit and vegetables on the streets in developing countries. They’re usually in debt to a moneylender in the market, who takes about half their profits each day as interest. Some of the women have figured a simple way to get out of debt and keep all their profits. But most of the women make a choice every day that keeps them in debt. How would these businesswomen behave, he wondered, if the slate was wiped clean? So he got a grant, paid off their debt, and waits to see what happens next.”

“R&D in the poverty space has huge potential returns and there is too little thinking about that.” – Sendhil Mullainathan